Naweed Syed's lab cultivated brain cells on a microchip.
The new technology from the lab of Naweed Syed, in coaction with the NRC, is published online this month in the journal, Biomedical Devices.
"This technical breakthrough means we can track subtle changes in brain activity at the grade of ion channels and synaptic potentials, which are likewise the most suitable target sites for drug development in neurodegenerative diseases and neuropsychological disorders," says Syed, professor and mind of the Department of Cell Biology and Anatomy, member of the Hotchkiss Brain Institute and adviser to the Vice President Research on Biomedical Engineering Initiative of the U of C.
The new neurochips are also automated, meaning that anyone can take to direct individual brain cells on them. Previously it took days of education to see how to record ion channel activity from brain cells, and it was just possible to monitor one or two cells simultaneously. Now, larger networks of cells can be located on a bit and discovered in minute detail, allowing the analysis of several brain cells networking and performing automatic, large-scale drug screening for various brain dysfunctions.
This new technology has the potentiality to serve scientists in a kind of fields and on a sort of research projects. Gerald Zamponi, professor and mind of the Section of Physiology and Pharmacology, and member of the Hotchkiss Brain Institute, says, "This technology can probably be scaled up such that it will go a new tool for medium throughput drug screening, in addition to its utility for basic biomedical research".
The University of Calgary, Faculty of Medicine scientists who proved it is potential to train a web of brain cells that reconnect on a silicon chip-or the head on a microchip-have developed new technology that monitors brain cell activity at a result never achieved before.
Developed with the National Research Council Canada (NRC),
No comments:
Post a Comment